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BMP8B, human recombinant protein

BMP8, OP2, Bone morphogenetic protein 8B

     
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  • CITATIONS
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Product info
Primary Accession P34820
Concentration 1
Calculated MW 18.1 kDa (162 aa, 264-402 aa + His tag), confirmed by MALDI-TOF.
Additional Info
Gene ID 656
Gene Symbol BMP8B
Other Names BMP8, OP2, Bone morphogenetic protein 8B
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MGSAVRPLRR RQPKKSNELP QANRLPGIFD DVHGSHGRQV CRRHELYVSF QDLGWLDWVI APQGYSAYYC EGECSFPLDS CMNATNHAIL QSLVHLMMPD AVPKACCAPT KLSATSVLYY DSSNNVILRK HRNMVVKACG CH
Target/Specificity BMP8B
Format Liquid
Storage -80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol
Citations (0)

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Background

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. Recombinant human BMP8B protein, fused to His-tag at N-terminus, was expressed in E.coli.

References

Oezkaynak E.,et al.J. Biol. Chem. 267:25220-25227(1992).
Onishi M.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).

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$ 295.00
Cat# PBV10928r
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