IL1F10, human recombinant protein
Putative interleukin-1 receptor antagonist FKSG75, FIL1-theta, FKSG75, IL1HY2
|Calculated MW||19.1 kDa (172 aa, 1-152 aa + His Tag), confirmed by MALDI-TOF.|
|Other Names||Putative interleukin-1 receptor antagonist FKSG75, FIL1-theta, FKSG75, IL1HY2|
|Sequence||MGSSHHHHHH SSGLVPRGSH MCSLPMARYY IIKYADQKAL YTRDGQLLVG DPVADNCCAE KICTLPNRGL DRTKVPIFLG IQGGSRCLAC VETEEGPSLQ LEDVNIEELY KGGEEATRFT FFQSSSGSAF RLEAAAWPGW FLCGPAEPQQ PVQLTKESEP SARTKFYFEQ SW|
|Storage||-80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol and 1 mM DTT.|
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IL1F10 is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. Recombinant human IL1F10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Bensen J.T.,et al.J. Interferon Cytokine Res. 21:899-904(2001).
Wang Y.-G.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Lin H.,et al.J. Biol. Chem. 276:20597-20602(2001).
Nicklin M.J.H.,et al.Genomics 79:718-725(2002).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
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