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CD68, human recombinant protein
Macrosialin, GP110, LAMP4, SCARD1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P34810 |
|---|---|
| Concentration | 1 |
| Calculated MW | 34.1 kDa (323 aa, 22-319 aa + His Tag), confirmed by MALDI-TOF. |
| Gene ID | 968 |
|---|---|
| Gene Symbol | CD68 |
| Other Names | Macrosialin, GP110, LAMP4, SCARD1 |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥85% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Sequence | MGSSHPLHHH SSGLVPRGSH MGSHMNDCPH KKSATLLPSF TVTPTVTEST GTTSHRTTKS HKTTTHRTTT TGTTSHGPTT ATHNPTTTSH GNVTVHPTSN STATSQGPST ATHSPATTSH GNATVHPTSN STATSPGFTS SAHPEPPPPS PSPSPTSKET IGDYTWTNGS QPCVHLQAQI QIRVMYTTQG GGEAWGISVL NPNKTKVQGS CEGAHPHLLL SFPYGHLSFG FMQDLQQKVV YLSYMAVEYN VSFPHAAQWT FSAQNASLRD LQAPLGQSFS CSNSSIILSP AVHLDLLSLR LQAAQLPHTG VFGQSFSCPS DRS |
| Target/Specificity | CD68 |
| Format | Liquid |
| Storage | -80°C; 1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 1 M Urea and 10% glycerol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Macrosialin, also known as CD68, is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. It is found in cytoplasmic granules and in the cytoplasm of various non-hematopoietic tissues including liver and kidney tubules and glomeruli. CD68 is also found, to a lesser extent, on the surface of macrophages, monocytes, neutrophils, basophils and large lymphocytes. Recombinant human CD68 protein, fused to His-tag at N-terminus, was expressed in E.coli.
References
Holness C.L.,et al.Blood 81:1607-1613(1993).
Kalnine N.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:1045-1049(2006).
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