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CD83, human recombinant protein

CD83 antigen isoform b precursor, BL11, HB15

     
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Product info
Primary Accession Q01151
Concentration 0.25
Calculated MW 16 kDa (148 aa, 20-144 aa + His Tag), confirmed by MALDI-TOF.
Additional Info
Gene ID 9308
Gene Symbol CD83
Other Names CD83 antigen isoform b precursor, BL11, HB15
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MGSTPEVKVA CSEDVDLPCT APWDPQVPYT VSWVKLLEGG EERMETPQED HLRGQHYHQK GQNGSFDAPN ERPYSLKIRN TTSCNSGTYR CTLQDPDGQR NLSGKVILRV TGCPAQRKEE TFKKYRAE
Target/Specificity CD83
Format Liquid
Storage -80°C; 0.25 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl and 30% glycerol.
Citations (0)

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Background

CD83 is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. Recombinant human CD83 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

References

Zhou L.-J.,et al.J. Immunol. 149:735-742(1992).
Kozlow E.J.,et al.Blood 81:454-461(1993).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).

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$ 375.00
Cat# PBV10968r-50
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