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CXCL4, human recombinant protein

Chemokine (C-X-C motif) ligand 4, PF4, MGC138298, SCYB4

     
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Product info
Primary Accession P02776
Concentration 0.25
Calculated MW 10.0 kDa (91 aa, 32-101 aa + His Tag), confirmed by MALDI-TOF.
Additional Info
Gene ID 5196
Gene Symbol CXCL4
Other Names Chemokine (C-X-C motif) ligand 4, PF4, MGC138298, SCYB4
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥85%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MEAEEDGDLQ CLCVKTTSQV RPRHITSLEV IKAGPHCPTA QLIATLKNGR KICLDLQAPL YKKIIKKLLE S
Target/Specificity CXCL4
Format Liquid
Storage -80°C; 0.25 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 2 mM DTT and 50% glycerol.
Citations (0)

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Background

CXCL4 is a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. Recombinant human CXCL4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

References

Poncz M.,et al.Blood 69:219-223(1987).
Eisman R.,et al.Blood 76:336-344(1990).
Zhang C.,et al.Blood 98:610-617(2001).
Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 295.00
Cat# PBV10970r
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