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FGF14, human recombinant protein

Fibroblast growth factor 14 isoform 1A, FGF-14, FHF-4, FHF4, SCA27

     
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  • CITATIONS
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Product info
Primary Accession Q92915
Concentration 0.25
Calculated MW 30.0 kDa (271 aa, 1-247 aa + His Tag), confirmed by MALDI-TOF.
Additional Info
Gene ID 2259
Gene Symbol FGF14
Other Names Fibroblast growth factor 14 isoform 1A, FGF-14, FHF-4, FHF4, SCA27
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MGSHMAAAIA SGLIRQKRQA REQHWDRPSA SRRRSSPSKN RGLCNGNLVD IFSKVRIFGL KKRRLRRQDP QLKGIVTRLY CRQGYYLQMH PDGALDGTKD DSTNSTLFNL IPVGLRVVAI QGVKTGLYIA MNGEGYLYPS ELFTPECKFK ESVFENYYVI YSSMLYRQQE SGRAWFLGLN KEGQAMKGNR VKKTKPAAHF LPKPLEVAMY REPSLHDVGE TVPKPGVTPS KSTSASAIMN GGKPVNKSKT T
Target/Specificity FGF14
Format Liquid
Storage -80°C; 0.25 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 5 mM DTT and 50% glycerol.
Citations (0)

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Background

FGF14 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. Recombinant human FGF14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

References

Smallwood P.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:9850-9857(1996).
Bonner T.I.,et al.Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
Chumakov I.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:13675-13680(2002).
Dunham A.,et al.Nature 428:522-528(2004).
van Swieten J.C.,et al.Am. J. Hum. Genet. 72:191-199(2003).

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$ 375.00
Cat# PBV10971r
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