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LGALS8, human recombinant protein

Gal-8, PCTA1, Po66-CBP, Prostate carcinoma tumor antigen 1

     
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Product info
Primary Accession O00214
Concentration 0.5
Calculated MW 37.9 kDa (337 aa, 1-317 aa + His Tag).
Additional Info
Gene ID 3964
Gene Symbol Lgals8
Other Names Gal-8, PCTA1, Po66-CBP, Prostate carcinoma tumor antigen 1
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MMLSLNNLQN IIYNPVIPFV GTIPDQLDPG TLIVIRGHVP SDADRFQVDL QNGSSMKPRA DVAFHFNPRF KRAGCIVCNT LINEKWGREE ITYDTPFKRE KSFEIVIMVL KDKFQVAVNG KHTLLYGHRI GPEKIDTLGI YGKVNIHSIG FSFSSDLQST QASSLELTEI SRENVPKSGT PQLRLPFAAR LNTPMGPGRT VVVKGEVNAN AKSFNVDLLA GKSKDIALHL NPRLNIKAFV RNSFLQESWG EEERNITSFP FSPGMYFEMI IYCDVREFKV AVNGVHSLEY KHRFKELSSI DTLEINGDIH LLEVRSW
Target/Specificity LGALS8
Format Liquid
Storage -80°C; 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 0.1 M NaCl and 10% glycerol.
Citations (0)

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Background

LGALS8, also known as prostate-specific membrane antigen (PCTA1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin gene family which mediates both cell-cell and cell matrix interactions in a manner similar to the selectin subgroup of C-type lectins. Recombinant human LGALS8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

References

Su Z.-Z.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:7252-7257(1996).
Hadari Y.R.,et al.Trends Glycosci. Glycotechnol. 9:103-112(1997).
Brichory F.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
Maier C.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Gopalkrishnan R.V.,et al.Oncogene 19:4405-4416(2000).

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$ 295.00
Cat# PBV10990r
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