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>   home   >   Products   >   Proteins   >   Human CellExp Kallikrein-4, human recombinant protein   

Human CellExp Kallikrein-4, human recombinant protein

KLK4, Kallikrein-4, Prostate, KLK-L1, EMSP1, PRSS17, PSTS

Product info
Primary Accession Q9Y5K2
Calculated MW This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 25.2 kDa. The predicted N-terminus is Ser 27. DTT-reduced Protein migrates as 30-32 kDa due to glycosylation.
Additional Info
Gene ID 9622
Gene Symbol KLK4
Other Names KLK4, Kallikrein-4, Prostate, KLK-L1, EMSP1, PRSS17, PSTS
Gene Source Human
Source HEK293 cells
Assay&Purity SDS-PAGE; ≥92%
Assay2&Purity2 N/A;
Recombinant Yes
Results Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. The specific activity is >200 pmoles / min / µg.
Target/Specificity Kallikrein-4
Application Notes Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Format Lyophilized
Storage -20°C; Lyophilized from 0.22 µm filtered solution in 50 mM Tris, 150 mM NaCl, pH 7.5. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Citations (0)

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Kallikrein-4 (KLK4) is also known as Enamel matrix serine proteinase 1 (EMSP1), Kallikrein-like protein 1 (KLK-L1), Prostase, Serine protease 17 (PRSS17), PSTS, which belongs to the peptidase S1 family and Kallikrein subfamily. KLK4 contains one peptidase S1 domain. KLK4 is expressed in prostate and involved in enamel formation. Defects in Kallikrein-4 / KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) which is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions.


Nelson P.S.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:3114-3119(1999).
Yousef G.M.,et al.Cancer Res. 59:4252-4256(1999).
Stephenson S.A.,et al.J. Biol. Chem. 274:23210-23214(1999).
Gan L.,et al.Gene 257:119-130(2000).
Hu J.C.-C.,et al.Gene 251:1-8(2000).

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$ 205.00
Cat# PBV11038r
(40 western blots)
Availability: 5-7days
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