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Human CellExp TNFRSF4/OX40 /CD134, human recombinant protein
TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P43489 |
|---|---|
| Calculated MW | This protein is fused with 6× his tag at the C-terminus, and has a calculated MW of 21 kDa. The predicted N-terminus is Leu 29. DTT-reduced Protein migrates as 35-48 kDa in SDS-PAGE due to glycosylation. |
| Gene ID | 7293 |
|---|---|
| Gene Symbol | TNFRSF4 |
| Other Names | TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L |
| Gene Source | Human |
| Source | HEK293 cells |
| Assay&Purity | SDS-PAGE; ≥92% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Results | Measured by its binding ability in a functional ELISA. Immobilized rh TNFRSF4 / OX40 / CD134 at 2 µg/ml (100 µl/well) can bind human TNFSF4 Fc Chimera. The EC50 of human TNFSF4 Fc Chimera is 30 ng/mL. |
| Target/Specificity | TNFRSF4/OX40 /CD134 |
| Application Notes | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C. |
| Format | Lyophilized |
| Storage | -20°C; Lyophilized from 0.22 µm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.
References
Latza U.,et al.Eur. J. Immunol. 24:677-683(1994).
Baum P.R.,et al.Circ. Shock 44:30-34(1994).
Pankow R.,et al.J. Immunol. 165:263-270(2000).
Gregory S.G.,et al.Nature 441:315-321(2006).
Arch R.H.,et al.Mol. Cell. Biol. 18:558-565(1998).
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