|Calculated MW||40.0 kDa|
|Other Names||AGP, Orosomucoid|
|Results||≥ 120 units/mg protein.|
|Target/Specificity||Alpha 1 Acid Glycoprotein|
|Storage||-20°C; Lyophilized as a salt free solid.|
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Provided below are standard protocols that you may find useful for product applications.
Found in human plasma in concentrations of 55-140 mg per 100 ml. Classical standard glycoprotein for studies on the structure of the oligosaccharide units. Carbohydrate content is 40%. Its biological significance is unknown although it can bind progesterone 15 times as strongly as albumin. Sialic-acid-deficient alpha-1-AG has an affinity for vitamin B-12. Clinically, alpha 1 acid glycoprotein is an acute-phase reactant that together with haptoglobin is an indicator of acute inflammation. The alpha 1 acid glycoprotein: haptoglobin ratio is useful in studies of bone marrow disorders, hemolytic processes and metastases.
Dente L.,et al.EMBO J. 6:2289-2296(1987).
Board P.G.,et al.Gene 44:127-131(1986).
Dente L.,et al.Nucleic Acids Res. 13:3941-3952(1985).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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