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Plasminogen, Human Plasma recombinant protein


Product info
Primary Accession P00747
Calculated MW 90.0 – 92.0 kDa
Additional Info
Gene ID 5340
Gene Symbol PLG
Other Names PLG
Gene Source Human
Source Human Plasma
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant No
Target/Specificity Plasminogen
Format Lyophilized
Storage -20°C; Lyophilized from 20 mM Tris-HCl, pH 7.5, with 2 mM EDTA.
Citations (0)

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Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. Plasminogen is the inactive precursor of plasmin. Plasminogen is activated by the action of either tissue plasminogen activator (tPA), which primarily activates the fibrinolytic (thrombolytic) activity of plasmin, or urokinase plasminogen activator (uPA), which is associated with extracellular matrix remodeling and cell migration. Plasmin cleaves fibrin/fibrinogen and blood coagulation factors V/Va and VIII/VIIIa. It activates matrix metalloproteinases by cleaving the inactive proenzymes. It is also involved in the activation of some growth factors, such as vascular endothelial growth factor (VEGF) and transforming growth factor β (TGF-β).


Petersen T.E.,et al.J. Biol. Chem. 265:6104-6111(1990).
Forsgren M.,et al.FEBS Lett. 213:254-260(1987).
Browne M.J.,et al.Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Sottrup-Jensen L.,et al.Submitted (JUL-1977) to the PIR data bank.

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$ 185.00
Cat# PBV11158r
(40 western blots)
Availability: 5-7days
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