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PEDF, mouse recombinant protein

Pigment Epithelium-derived Factor; Stromal Cell-derived Factor 3; Serpin F1; Caspin

Product info
Primary Accession P97298
Calculated MW ~47.0 kDa. Mouse PEDF (aa 20-417) is fused at the C-terminus to a FLAG®-tag.
Additional Info
Gene ID 20317
Gene Symbol Serpinf1
Other Names Pigment Epithelium-derived Factor; Stromal Cell-derived Factor 3; Serpin F1; Caspin
Gene Source Mouse
Source CHO cells
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Target/Specificity PEDF
Application Notes Reconstitute with 100 µl sterile distilled water.
Format Lyophilized
Storage -20°C; Lyophilized in PBS.
Citations (0)

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Pigment epithelium-derived factor (PEDF) is a 47 kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and fetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.


Shirozu M.,et al.Genomics 37:273-280(1996).
Kozaki K.,et al.J. Biol. Chem. 273:15125-15130(1998).
Singh V.K.,et al.Mol. Vis. 4:7-7(1998).
Tombran-Tink J.,et al.Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Abramson L.P.,et al.J. Pediatr. Surg. 38:336-342(2003).

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$ 295.00
Cat# PBV11181r
(40 western blots)
Availability: 5-7days
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