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Human CellExp UNC5B, human recombinant protein

Netrin Receptor UNC5B; UNC5H2; Protein Unc-5 Homolog 2; Protein Unc-5 Homolog B; p53-regulated Recep

     
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Product info
Primary Accession Q8IZJ1
Calculated MW ~80.0 kDa. The extracellular region of human UNC5B (aa 28-363) is fused at the C-terminus to the Fc portion of human IgG1.
Additional Info
Gene ID 219699
Gene Symbol UNC5B
Other Names Netrin Receptor UNC5B; UNC5H2; Protein Unc-5 Homolog 2; Protein Unc-5 Homolog B; p53-regulated Receptor for Death and Life Protein 1
Gene Source Human
Source HEK293 cells
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Target/Specificity UNC5B
Application Notes Reconstitute with 50 µl sterile distilled water.
Format Lyophilized
Storage -20°C; Lyophilized in PBS.
Citations (0)

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Background

UNC5B is a receptor for the netrin family of guidance molecules. It was identified as a mediator of the repulsive response in neurons and it is the only known netrin receptor with prominent endothelial expression. It has an important role in angiogenesis signaling.

References

Komatsuzaki K.,et al.Biochem. Biophys. Res. Commun. 297:898-905(2002).
Tanikawa C.,et al.Nat. Cell Biol. 5:216-223(2003).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).

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$ 195.00
Cat# PBV11185r-10
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