|Calculated MW||~35.0 kDa. Mouse meteorin-like (46-311) is fused at the N-terminus to a FLAG®-tag.|
|Other Names||Metrnl, Subfatin, Cometin|
|Application Notes||Reconstitute with 100 µl sterile distilled water.|
|Storage||-20°C; Lyophilized in PBS.|
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Provided below are standard protocols that you may find useful for product applications.
Meteorin-like (cometin; subfatin) is a potent new neurotrophic factor promoting neurite outgrowth from dorsal root ganglion cells. Meteorin-like is also a novel adipokine expressed by adipose tissue being downregulated upon caloric restriction. Meteorin-like is secreted by muscles during exercise and converts white adipose cells into brown fat tissue.
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Rao R.R.,et al.Cell 157:1279-1291(2014).
Li Z.Y.,et al.CNS Neurosci. Ther. 20:344-354(2014).
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