TGF-β3, Mouse recombinant protein
Transforming growth factor beta-3
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P04202 |
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Concentration | 0.25 |
Calculated MW | 25.5 kDa. |
Gene ID | 21803 |
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Gene Symbol | TGF-beta-1 |
Other Names | Transforming growth factor beta-3 |
Gene Source | Mouse |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥98% |
Assay2&Purity2 | N/A; |
Recombinant | Yes |
Sequence | ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS |
Target/Specificity | TGF-beta-1 |
Format | Liquid |
Storage | -80°C; 0.25 mg/mL solution containing 20% ethanol and 0.12% acetic acid (AcOH) |
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Provided below are standard protocols that you may find useful for product applications.
Background
The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-β isoforms (TGF-β1, -β2 and –β3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-β3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-β3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis. Recombinant mouse TGF-β3 is a non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains, with a total molecular weight of 25.5 kDa.
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