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PDGFR beta, Active recombinant protein

PDGR. platelet-derived growth factor receptor, beta polypeptide

Product info
Primary Accession P09619
Concentration 0.1
Calculated MW 96.0 kDa
Additional Info
Gene ID 5159
Gene Symbol PDGFRB
Other Names PDGR. platelet-derived growth factor receptor, beta polypeptide
Source Baculovirus (Sf9 insect cells)
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -80°C; Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Citations (0)

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PDGFRb (platelet-derived growth factor receptor b) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. PDGFRb deficient mice are hemorrhagic, severely anemic and exhibit a defect in kidney glomeruli function (1). However, absence of PDGFRb has no impact on major blood vessels and the heart. PDGFRb expression and activity is elevated in several cancers and inhibition of PDGFRb activity blocks progression of renal carcinoma in an animal model (2).

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$ 295.00
Cat# PBV11341r
(40 western blots)
Availability: 5-7days
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