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TIMP-2, human fibroblasts recombinant protein
Tissue Inhibitor of Matrix Metalloproteinases – 2
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P16035 |
|---|---|
| Concentration | 0.1 |
| Calculated MW | 21.0 kDa |
| Gene ID | 7077 |
|---|---|
| Gene Symbol | TIMP2 |
| Other Names | Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2) |
| Gene Source | Human |
| Source | Isolated from human fibroblasts |
| Assay&Purity | SDS-PAGE; ≥90% |
| Assay2&Purity2 | HPLC; |
| Recombinant | No |
| Format | Liquid |
| Storage | -80°C; In 50 mM Tris-HCl, pH 7; 200 mM NaCl; 5 mM CaCl₂; 1 µM ZnCl₂; 0.05% Brij 35; 0,05% NaN₃ |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Glycoprotein that belongs to a family which takes part in the activation and regulation of the MMP-activity. Forms a non-covalent stoichiometric complex with latent and active MMP's. Inhibits the activities of MMP-1, MMP-2, MMP-12 and transin.
References
Stetler-Stevenson W.G.,et al.J. Biol. Chem. 265:13933-13938(1990).
Boone T.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:2800-2804(1990).
Hammani K.,et al.J. Biol. Chem. 271:25498-25505(1996).
Malik K.,et al.Submitted (AUG-1990) to the EMBL/GenBank/DDBJ databases.
Stetler-Stevenson W.G.,et al.J. Biol. Chem. 264:17374-17378(1989).
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