Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Proteins   >   Cytochrome P450 2D6, human recombinant protein   

Cytochrome P450 2D6, human recombinant protein

Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2DL1, P4

Product info
Primary Accession P10635
Concentration Lot specific
Calculated MW 55 kDa
Additional Info
Gene ID 1565
Gene Symbol CYP2D6
Other Names Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1
Gene Source Human
Source Sf9 Insect cells
Assay&Purity SDS-PAGE; Glycosylated, so purity ≥40%
Assay2&Purity2 N/A;
Recombinant Yes
Target/Specificity Cytochrome P450 2D6
Application Notes In 50 mM Potassium phosphate buffer pH 7.5, 15% glycerol, 1 mM DTT and 1% Triton X-100
Format Liquid
Storage -20°C; Sterile filtered, 50 mM Potassium phosphate buffer pH 7.5, 15% glycerol, 1 mM DTT and 1% Triton X-100
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


Cytochrome P450 2D6 is a member of a family of microsomal enzymes (mono-oxygenases) present in the endoplasmic reticulum membrane, which detoxify xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the "liver kidney microsomal antigen 1" (LKM 1) which has been classically studied by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2; LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques.


Gonzalez F.J.,et al.Genomics 2:174-179(1988).
Gonzalez F.J.,et al.Nature 331:442-446(1988).
Kimura S.,et al.Am. J. Hum. Genet. 45:889-904(1989).
Gaedigk A.,et al.Pharmacogenomics J. 5:173-182(2005).
Gaedigk A.,et al.Pharmacogenomics J. 5:276-276(2005).

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 155.00
$ 385.00
$ 5,250.00
Cat# PBV11415r
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions