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Caspases Group II, Activ Human recombinant protein

Caspases Group II, Active Human

Product info
Primary Accession P55210
Calculated MW 34277 Da
Additional Info
Gene ID CASP2- 835 CASP3- 836 CASP7- 840
Gene Symbol CASP2 CASP3 CASP7
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE;
Assay2&Purity2 HPLC;
Recombinant Yes
Application Notes Reconstitute to 1 unit per µl in PBS.
Format Lyophilized
Storage -70°C; Lyophilized powder
Citations (0)

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Caspase family consists of more than 10 members. Based on their extended substrate specificities, these enzymes were divided into three major groups: Group I (contains caspase-1,-4,-5), Group II (contains caspase-2,-3,-7), and Group III (contains caspase-6,-8,-9,-10). Evidences have suggested that Group I caspases are involved primarily in the production of inflammatory cytokines, while group II and III enzymes function in apoptosis as effectors and upstream activators, respectively. The group caspases were expressed in E. coli and routinely tested for their ability to enzymatically cleave the substrate VDVAD-pNA (for caspase-2) and DEVD-pNA (for caspase-3 & -7).


Fernandes-Alnemri T.,et al.Cancer Res. 55:6045-6052(1995).
Duan H.,et al.J. Biol. Chem. 271:1621-1625(1996).
Lippke J.A.,et al.J. Biol. Chem. 271:1825-1828(1996).
Juan T.S.-C.,et al.Genomics 40:86-93(1997).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

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$ 325.00
Cat# PBV11433r
(40 western blots)
Availability: 5-7days
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