AIF1 (His-tagged), human recombinant
Allograft inflammatory factor 1, Ionized calcium-binding adapter molecule 1, Protein G1, IBA1
|Calculated MW||18.9 kDa|
|Other Names||Allograft inflammatory factor 1, Ionized calcium-binding adapter molecule 1, Protein G1, IBA1|
|Sequence||Met 1 - Pro 147|
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Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
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