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Human CellExp™ Biotinylated Fc gamma RI/CD64, human recombinant
High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RI, FcRI, Fc-gamma RIA
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P12314 |
|---|---|
| Calculated MW | The protein has a calculated MW of 34.3 kDa. The reducing (R) protein migrates as 45-60 kDa in SDS-PAGE due to glycosylation. |
| Gene ID | 2209 |
|---|---|
| Other Names | High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RI, FcRI, Fc-gamma RIA, FcgammaRIa, CD64 , FCGR1A |
| Gene Source | Human |
| Source | HEK 293 cells |
| Assay&Purity | SDS-PAGE;≥92% |
| Recombinant | Yes |
| Sequence | Gln 16 – Pro 288 |
| Target/Specificity | Fc gamma RI |
| Application Notes | Reconstitute in sterile deionized water to a stock solution of 200 µg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage. |
| Format | Dry powder |
| Storage | -20°C;Lyophilized powder |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses.
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