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>   home   >   Products   >   Proteins   >   Human CellExp™ GITR / TNFRSF18, Human recombinant   

Human CellExp™ GITR / TNFRSF18, Human recombinant

AITR, GITR, TNFRSF18, CD357

     
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Product info
Primary Accession Q9Y5U5-1
Calculated MW This protein is fused with a 6× His tag at C-terminus and has a calculated MW of 15.4 kDa. The protein migrates as 22-25 kDa in SDS-PAGE due to glycosylation.
Additional Info
Other Names AITR, GITR, TNFRSF18, CD357
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE;≥92%
Assay2&Purity2 N/A;≥92%
Recombinant Yes
Target/Specificity GITR
Application Notes Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml
Format Lyophilized
Storage -20°C;Lyophilized from 0.22 µm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Citations (0)

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Background

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

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$ 200.00
$ 610.00
Cat# PBV11475r-10
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