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CSTB, human recombinant

Cystatin-B, Stefin B, PME, CST6

     
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Product info
Primary Accession NP_000091
Concentration 1 mg/ml
Calculated MW This protein is fused with a 6× His tag at N-terminus and has a calculated MW of 13 kDa.
Additional Info
Other Names Cystatin-B, Stefin B, PME, CST6
Gene Source Human
Source E.coli
Assay&Purity SDS-PAGE;>95%
Assay2&Purity2 N/A;>95%
Recombinant Yes
Sequence MGSSHHHHHH SSGLVPRGSH MMCGAPSATQ PATAETQHIA DQVRSQLEEK ENKKFPVFKA VSFKSQVVAG TNYFIKVHVG DEDFVHLRVF QSLPHENKPL TLSNYQTNKA KHDELTYF
Target/Specificity CSTB
Application Notes In 20 mM Tris-HCl buffer (pH8.0) containing 50mM NaCl.
Format Liquid
Storage -20°C;Liquid
Citations (0)

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Background

CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to form a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes. In cells, CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus.

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$ 180.00
$ 335.00
Cat# PBV11479r-10
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