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>   home   >   Products   >   Proteins   >   Human CellExp™ CD45, human recombinant   

Human CellExp™ CD45, human recombinant

LCA; LY5; B220; T200; CD45R; GP180; PTPRC

     
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Product info
Primary Accession P08575
Calculated MW 65kDa
Additional Info
Gene ID 5788
Other Names LCA; LY5; B220; T200; CD45R; GP180; PTPRC
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE;≥ 98%
Recombinant Yes
Target/Specificity PTPRC
Application Notes Reconstitute in 1X PBS to the desired protein concentration.
Format Lyophilized
Storage -20°C;Lyophilized from 0.2 µm-filtered solution in PBS.
Citations (0)

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Background

Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. CD45 is found expression specifically in hemotopietic cells. CD45 consists of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. It serves as an essential regulator of T-cell and B-cell antigen receptor signaling through either direct interaction with components of the antigen receptor complexs or by activating various Src family kinases required for the antigen receptor signaling and it also can suppress JAK kinases.

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$ 185.00
$ 375.00
Cat# PBV11492r-10
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