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Prostatic acid phosphatase, human recombinant
PAP, 5'-nucleotidase, ACPP, 5’-NT, ACP-3, ACP3
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P15309 |
|---|---|
| Concentration | 0.5 mg/ml |
| Calculated MW | 41.8 kDa |
| Gene ID | 55 |
|---|---|
| Other Names | PAP, 5'-nucleotidase, ACPP, 5’-NT, ACP-3, ACP3 |
| Gene Source | Human |
| Source | Baculovirus |
| Assay&Purity | SDS-PAGE;> 95% |
| Recombinant | Yes |
| Sequence | KELKFVTLVF RHGDRSPIDT FPTDPIKESS WPQGFGQLTQ LGMEQHYELG EYIRKRYRKF LNESYKHEQV YIRSTDVDRT LMSAMTNLAA LFPPEGVSIW NPILLWQPIP VHTVPLSEDQ LLYLPFRNCP RFQELESETL KSEEFQKRLH PYKDFIATLG KLSGLHGQDL FGIWSKVYDP LYCESVHNFT LPSWATEDTM TKLRELSELS LLSLYGIHKQ KEKSRLQGGV LVNEILNHMK RATQIPSYKK LIMYSAHDTT VSGLQMALDV YNGLLPPYAS CHLTELYFEK GEYFVEMYYR NETQHEPYPL MLPGCSPSCP LERFAELVGP VIPQDWSTEC MTTNSHQGTE DSTDHHHHHH |
| Target/Specificity | ACPP |
| Format | Liquid |
| Storage | -20°C;In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol |
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Provided below are standard protocols that you may find useful for product applications.
Background
ACPP, also known as prostatic acid phosphatase isoform PAP, is a type I integral membrane protein of the plasma membrane and lysosomes, and a secreted form also exists. The concentration of ACPP is elevated in the circulation of prostate cancer patients, making the enzyme a marker for the progression of prostate cancer. Recombinant human ACPP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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