|Calculated MW||7.5 kDa|
|Other Names||TNFRSF17, CD269, BCM, BCMA|
|Source||HEK 293 cells|
|Application Notes||Reconstitute in sterile deionized water to a concentration of 50 µg/ml.|
|Storage||-20°C;Lyophilized from 0.22 µm filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.|
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Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
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