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Human CellExp™ TROP-2 / TACSTD2, Human recombinant
TACSTD2, GA733-1, M1S1, TROP2
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P09758 |
|---|---|
| Calculated MW | 28.7 kDa |
| Gene ID | 4070 |
|---|---|
| Other Names | TACSTD2, GA733-1, M1S1, TROP2 |
| Gene Source | Human |
| Source | HEK 293 cells |
| Assay&Purity | SDS-PAGE;> 95% |
| Recombinant | Yes |
| Target/Specificity | TACSTD2 |
| Application Notes | Reconstitute in sterile deionized water to the desired protein concentration. |
| Format | Lyophilized |
| Storage | -20°C;Lyophilized from 0.22 µm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Tumor-associated calcium signal transducer 2 (TACSTD2) is also known as Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1 (M1S1), Pancreatic carcinoma marker protein GA733-1, which belongs to the EPCAM family. TACSTD2 contains one thyroglobulin type-1 domain. TACSTD2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. TACSTD2 transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of TACSTD2 result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness
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