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>   home   >   Products   >   Proteins   >   Human CellExp™ VEGF-D, Human recombinant    

Human CellExp™ VEGF-D, Human recombinant

FIGF, VEGFD

     
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Product info
Primary Accession O43915
Calculated MW 13 kDa
Additional Info
Gene ID 2277
Other Names FIGF, VEGFD
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE;> 95%
Recombinant Yes
Target/Specificity VEGFD
Application Notes Reconstitute in sterile deionized water to the desired protein concentration.
Format Lyophilized
Storage -20°C;Lyophilized from 0.22 µm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
Citations (0)

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Background

Vascular endothelial growth factor D (VEGF-D) is also known as C-fos induced growth factor (FIGF), which belongs to the PDGF / VEGF growth factor family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. This secreted protein VEGF-D / FIGF undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3. The structure and function of this protein is similar to those of VEGFC. FIGF / VEGF-D is highly expressed in lung, heart, small intestine and fetal lung. FIGF / VEGF-D may function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR / FLK1) and VEGFR-3 (FLT4) receptors.

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$ 315.00
Cat# PBV11613r-10
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