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>   home   >   Products   >   Peptides   >   Synthetic Peptides   >   Cerebellin   


Synthetic Peptide

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P63181
Other Accession Q9R171, P63182, P86437, P23435
Calculated MW 1632.69 Da
Additional Information
Other Names Cerebellin-1, Precerebellin, Cerebellin, CER, [des-Ser1]-cerebellin, Cbln1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCerebellin is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Cbln1
Function Required for synapse integrity and synaptic plasticity. During cerebellar synapse formation, essential for the formation and maintenance of parallel fiber and Purkinje cell synapses. When parallel fibers make contact with Purkinje spines, CBLN1 interaction with GRID2 triggers the recruitment of NRXN1 and secretory vesicles to the sites of contact. NRXN1-CBLN1-GRID2 signaling induces presynaptic morphological changes, which may further accumulate pre- and postsynaptic components to promote bidirectional maturation of parallel fiber - Purkinje cell functionnally active synapses by a positive feedback mechanism. Required for CBLN3 export from the endoplasmic reticulum and secretion (By similarity).
Cellular Location Secreted. Cell junction, synapse, postsynaptic cell membrane
Tissue Location Localized in the Purkinje cells. Cerebellin and [des-Ser1]-cerebellin are equally abundant
Research Areas
Citations (0)

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Cat# SP2095a
(40 western blots)
Availability: Inquire
Bulk Size
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