|Calculated MW||4095.55 Da|
|Other Names||Exendin-1, Helospectin-1, VIP-like 1, Exendin-1b, Helospectin-2, EXE1|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Helospectin I is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||O-linked and free exendin-1 and exendin-1b have vasoactive intestinal peptide(VIP)/secretin-like biological activities. They interact with rat and human VIP receptors 1 (VIPR1) and 2 (VIPR2), with the highest affinity for the human VIPR2. They induce hypotension that is mediated by relaxation of cardiac smooth muscle.|
|Tissue Location||Expressed by the venom gland.|
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