|Calculated MW||1716.98 Da|
|Other Names||Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1, Cyclic AMP-responsive DNA-binding protein, CREB1, CREB, CREB2|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CREBtide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.|
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